冠状动脉前降支弥漫性长病变的雷帕霉素洗脱支架治疗
张利彬;甘舜进;张海滨;张学坤;郭金城;张立新;高国旺;
摘要(Abstract)：
目的探讨冠状动脉前降支弥漫性长病变雷帕霉素洗脱支架治疗的疗效。方法选取经冠状动脉造影证实为冠状动脉前降支弥漫性长病变患者178例,根据造影结果对患者行经皮冠状动脉成形术和雷帕霉素洗脱支架置入术。结果 178例患者中,介入治疗成功174例,成功率为97.8%,支架完全覆盖靶病变,扩张满意,血管腔残余狭窄<20%,TIMI血流3级达到率97.8%。随访12个月,发生心血管事件13例,其中非致死性心肌梗死3例,心绞痛复发10例。其中靶病变血运重建3例,药物保守治疗10例,无死亡病例。结论冠状动脉前降支弥漫性长病变患者行雷帕霉素洗脱支架治疗安全有效,能改善患者的近期和中期预后。
关键词(KeyWords)： 冠状动脉;前降支;雷帕霉素支架
基金项目(Foundation):
作者(Author): 张利彬;甘舜进;张海滨;张学坤;郭金城;张立新;高国旺;
Email:
DOI:
参考文献(References)：
- 1Moes JW,Leon MB,Popma JJ,et al.Sirolimus-eluting stentgs ver-sus standard stents in patients with stenosis in a native coronary artery[J].N Engl J med,2003,349:1315-1325.
- 2Bauters C,Hubert E,Part A,et al.Predictors of restenosis after cor-nery stent implatation[J].J Am Coll Cardiol,1998,31:1291-1293.
- 3Hausleiter J,sebastion M,Li AN,et al.A porcine coronary stent model of increased neotntima formation in the left anterior descending cornary arter[J].J Cardiol,2002,91:614-616.
- 4Shen W,zhang R,shen Y,et al.Optimal timing of coronary stenting in unstable agina patients[J].Chin Med J(Engl),2001,114(1):59-61.
- 5Schofer J,schluter M,Gershlick AH,et al.Sirdimus-eluting for treatment of patients with long atherosclerotic lesions in small coronary arteries:double-blind randomized controlled trial(E-SIRUS)[J].Lancet,2003,362:1093-1099.
- 6Schampaert E,Cohen EA,schluter M,et al.The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions mallnative coronary arteries(C-Smros)[J].J AM Coll Car-diol,2004,43:1110-1115.
- 7Sousa JE,Costa M,Abizaid A,et al.four-year angiographic and in-travascular ultrasound fllow-up of patients treated with sirolimus-elu-ting stents[J].Circulation,2005,111:2326-2329.
文章评论(Comment)：
|
||||||||||||||||||
|
||||||||||||||||||