卡维地洛治疗原发性高血压80例临床疗效观察The curative effect of carvedilol for essential hypertension
康岩;
摘要(Abstract)：
目的评价卡维地洛对原发性高血压的临床疗效及安全性。方法80例原发性高血压患者,经过2周安慰剂洗脱期后随即分为治疗组和对照组,对照组40例给予美托洛乐25mg,bid,口服两周末血压下降未达到有效标准者增至50mg,bid,疗程8周;治疗组40例给予卡维地洛10mg,bid,疗程共8周。结果治疗组降压总有效率80.0%,显效率52.5%,对照组总有效率77.5%,显效率50.0%;两组疗效比较无显著性差异(P>0.05),不良反应发生率亦无显著性差异(P>0.05),而且程度较轻可耐受。结论卡维地洛是治疗高血压安全有效的药物。
关键词(KeyWords)： 原发性高血压;卡维地洛;美托洛尔
基金项目(Foundation):
作者(Author): 康岩;
Email:
DOI:
参考文献(References)：
- 1Rider PM,Vaughan DE,Stanpfer MJ,et al.Endogenous tissuetype plasminogen activator and risk of myocardial infarction[J].Lancet,1993,34(1):1165-1169.
- 2Jansson JH,ohansson B,Boman K,et al.Hypofibrinolysis Patientswith hypertension and elevated cholesterlo[J].J Int Med,1999,98(1):229.
- 3Vaughan DE,Lazos SA,Tong K,et al.AngiotensinLL regulatesexpression of plasminogen activator inhibitor-1in cultured en-dothelialeels[J].J Clin Invest,1995,95(2):995-998.
- 4Markh A,Goa KL.Valsartan,a review of its pharmacology and therapeuuse in essential hypertension[J].Drujs,1997,54(2):299-301.
- 5Ernesto L,Jeong BP,Hope D,et al.Corporation of arterial struc-ture and endothelial dysfunction in human essential hypertensionby theangiotensin receptor antagonist losartsn[J].Circulations,2000,101(14):1635-1659.
文章评论(Comment)：
|
||||||||||||||||||
|
||||||||||||||||||