苏豪;苏华;杜优优;

• 1:北京中国航空中心医院心内科
• 2:中南大学附属湘雅二医院心内科
• 3:中南大学附属湘雅二医院心内科

摘要(Abstract)：

目的评价原发性高血压(EH)患者运动负荷试验结束后第3min收缩压恢复率(3rdM-SBPRR)和冠状动脉病变程度的关系及其对左主干狭窄的预测价值。方法对560个在3个月内完成了冠状动脉造影和运动负荷试验的EH患者按3rdM-SBPRR水平分为4个百分位数组,对各组间不同冠状动脉病变支数的百分率进行χ2检验。以受试者工作曲线(ROC)来分析3rdM-SBPRR预测左主干狭窄的临床意义。结果按照3rdM-SBPRR水平将患者分为4个百分位数组,P76~P100(1.13~1.42)组三支冠状动脉病变比率显著高于P1~P25(0.73~0.86)组、P26~P50(0.87~0.99)组和P51~P75(1.00~1.12)组,而单支冠状动脉病变比率显著低于上述3组;Gensini积分随着3rdM-SBPRR水平的升高而增高,且P76~P100(1.13~1.42)组显著高于其他3组。受试者工作曲线分析示3rdM-SBPRR用于判断左主干狭窄有显著意义(P=0.000),3rdM-SBPRR水平越高则左主干狭窄的可能性越大;3rdM-SBPRR水平为1.12时,其预测左主干狭窄的灵敏度为84.1%,特异度为78.1%。结论在EH患者其3rdM-SBPRR水平越高,则冠状动脉病变程度越重,3rdM-SBPRR可作为预测EH患者左主干狭窄的一个有效指标。

关键词(KeyWords)： 高血压;运动负荷试验;冠状动脉;诊断;血压

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作者(Author): 苏豪;苏华;杜优优;

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