血清脂联素水平及踝臂指数与冠状动脉病变程度的相关性研究Correlation Analysis of Plasma Adiponectin Concentration,Ankle Brachial Index and the Severity of Coronary Artery Lesion
牛新艳;
摘要(Abstract)：
目的观察冠心病(CHD)患者血清脂联素(APN)水平,踝臂指数(ABI),探讨其与冠状动脉病变程度之间的关系。方法将86例拟诊CHD并接受冠状动脉造影的患者分为急性冠状动脉综合征(ACS)组29例、稳定型心绞痛(SAP)组36例、对照组21例,采用酶联免疫吸附法(ELISA)测定APN水平,测量所有患者的ABI。结果 ACS组、SAP组的APN水平均低于正常对照组(P<0.05),ACS组的APN水平低于SAP组(P<0.05),2支、多支病变组ABI水平明显低于1支病变组和对照组,差异有统计学意义(P<0.05)。结论 APN是CHD的一个保护性因子,APN可以增加斑块的稳定性,减少ACS的发生;ABI与冠状动脉病变程度明显相关,APN与ABI联合检测在评估CHD患者冠状动脉病变程度方面有重要意义。
关键词(KeyWords)： 冠心病;急性冠状动脉综合征;心绞痛;脂联素;踝臂指数
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作者(Author): 牛新艳;
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参考文献(References)：
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