王国忠;张立新;张学坤;刘长虹;张海滨;郭金成;姚立云;高国旺;张正海;

• 1:北京市通州区潞河医院心内科

摘要(Abstract)：

目的评价急诊经皮冠状动脉介入治疗(PCI)术联合应用凯时(前列腺素E1)对术后心肌灌注的影响。方法将58例接受急诊PCI治疗且符合术前梗死相关血管完全闭塞(血流TIMI0级或1级),PCI治疗后梗死相关血管达到血流TIMI3级的急性心肌梗死患者随机分为凯时组28例和对照组30例。比较两组临床特征、心肌呈色分级(MBG)、心电图ST段回落指数(sumSTR)及住院期间主要心血管事件、左室射血分数。结果两组基础临床情况及造影特征无明显差异。凯时组心肌呈色分级2/3级获得率明显增高(71.4%vs43.3%,P<0.05),术后心电图ST段回落指数(sumSTR)≥50%的比例更高(82.1%vs53.3%,P<0.05)。心肌梗死1周后射血分数亦高于对照组(57.3%±5.4%vs47.2%±7.2%,P<0.05)。两组住院期间主要心血管事件差异无统计学意义(P>0.05)。结论急性心肌梗死患者在急诊PCI基础上,联合凯时治疗可改善心肌灌注,改善患者心功能,近期疗效好,无不良反应。

关键词(KeyWords)： 心肌梗死;经皮冠状动脉介入治疗;凯时;心肌灌注

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 王国忠;张立新;张学坤;刘长虹;张海滨;郭金成;姚立云;高国旺;张正海;

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