血浆脂联素水平与糖尿病患者冠状动脉粥样硬化的相关性研究Correlation between the level of plasma adiponectin and coronary arteriosclerosis in Diabetes
王旭;叶振梅;石长英;杨文生;单东风;张金娣;
摘要(Abstract):
目的探讨脂联素水平与糖尿病患者冠状动脉粥样硬化病变程度的相关性。方法根据冠状动脉造影结果将临床诊断为急性冠脉综合征的283例患者进行分组,应用放射免疫法检测血浆脂联素水平,同时监测血压、血糖、血浆胰岛素、血脂等相关指标。结果⑴脂联素水平与HDL-C、空腹血糖、胰岛素抵抗指数显著相关。⑵糖尿病组血浆脂联素水平明显高于非糖尿病组。⑶糖尿病患者冠状动脉粥样硬化程度随血浆脂联素水平进行性降低。结论低血浆脂联素水平是糖尿病患者冠状动脉粥样硬化发生发展的独立危险因素。
关键词(KeyWords): 脂联素;胰岛素抵抗指数;冠状动脉粥样硬化;定量冠状动脉造影分析;2型糖尿病
基金项目(Foundation):
作者(Author): 王旭;叶振梅;石长英;杨文生;单东风;张金娣;
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参考文献(References):
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