非梗阻性肥厚型心肌病并持续性心房颤动患者规范口服抗凝药物治疗出现多系统栓塞一例报道Multisystem Embolism in Spite of Treatment of Standardized Oral Anticoagulants in a Non-obstructive Hypertrophic Cardiomyopathy Patient Complicated with Persistent Atrial Fibrillation
李晓霞;宋康兴;
摘要(Abstract):
肥厚型心肌病患者心房颤动发生率较高,而并发心房颤动的肥厚型心肌病患者卒中及系统性栓塞发生风险明显升高。本文报道了1例在规范口服抗凝药物(包括达比加群、华法林、利伐沙班)基础上仍先后出现脑、肠系膜上动脉、肾动脉、右冠状动脉栓塞的非梗阻性肥厚型心肌病并持续性心房颤动患者,以期提高临床医生对该类患者栓塞风险及左心耳血栓形成的认识。
关键词(KeyWords): 心肌病,肥厚性;心房颤动;栓塞;病例报告
基金项目(Foundation):
作者(Author): 李晓霞;宋康兴;
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参考文献(References):
- [1]KUBO T,KITAOKA H,OKAWA M,et al.Clinical impact of atrial fibrillation in patients with hypertrophic cardiomyopathy.Results from Kochi RYOMA study[J].Circ J,2009,73(9):1599-1605.DOI:10.1253/circj.cj-09-0140
- [2]LEE S E,PARK J K,UHM J S,et al.Impact of atrial fibrillation on the clinical course of apical hypertrophic cardiomyopathy[J].Heart,2017,103(19):1496-1501.DOI:10.1136/heartjnl-2016-310720.
- [3]OLIVOTTO I,CECCHI F,CASEY S A,et al.Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy[J].Circulation,2001,104(21):2517-2524.DOI:10.1161/hc4601.097997.
- [4]柯旭,王帅,康琪,等.肥厚型心肌病并心房颤动未进行规范化抗凝治疗致血栓栓塞一例报道[J].实用心脑肺血管病杂志,2019,27(9):118-120.
- [5]肖敏.心尖肥厚型心肌病与冠心病的心电图对比分析[J].实用心脑肺血管病杂志,2013,21(5):88-89.DOI:10.3969/j.issn.1008-5971.2013.05.043.
- [6]ROWIN E J,HAUSVATER A,LIKN M S,et al.Clinical profile and consequences of atrial fibrillation in hypertrophic cardiomyopathy[J].Circulation,2017,136(25):2420-2436.DOI:10.1161/CIRCULATIONAHA.117.029267.
- [7]KIRCHHOF P,BENUSSI S,KOTECHA D,et al.2016 ESCGuidelines for the management of atrial fibrillation developed in collaboration with EACTS[J].Eur Heart J,2016,37(38):2893-2962.DOI:10.1093/eurheartj/ehw210.
- [8]ELLIOTT P M,ANASTASAKIS A,BORGER M A,et al.2014ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy:the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology(ESC)[J].Eur Heart J,2014,35(39):2733-2779.DOI:10.1093/eurheartj/ehu284.
- [9]JANUARY C T,WANN L S,ALPERT J S,et al.2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation:a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society[J].J Am Coll Cardiol,2014,64(21):2305-2307.DOI:10.1016/j.jacc.2014.03.022.
- [10]NOSEWORTHY P A,YAO X,SHAH N D,et al.Stroke and bleeding risks in N0AC-and warfarin-treated patients with hypertrophic cardiomyopathy and atrial fibrillation[J].J Am Coll Cardiol,2016,67(25):3020-3021.DOI:10.1016/j.jacc.2016.04.026.
- [11]利伐沙班临床应用中国专家组.利伐沙班应用中国专家建议-非瓣膜病心房颤动卒中预防分册[J].中华内科杂志,2013,52(10):897-902.DOI:10.3760/cma.j.issn.0578-1426.2013.10.031.
- [12]中华医学会心血管病学分会,中华医学会心电生理和起搏分会,中国医师协会心律学专业委员会.非瓣膜病心房颤动患者新型口服抗凝药的应用中国专家共识[J].中华心律失常学杂志,2014,18(5):321-329.DOI:10.3760/cma.j.issn.1007-6638.2014.05.001.
- [13]王涛,赵烨,惠杰.左心耳封堵术-预防心房颤动血栓形成新手段[J].浙江医学,2019,41(9):963-966.DOI:10.12056/j.issn.1006-2785.2019.41.9.2017-2865.
- [14]罗伟生,郭盛,林明宽.持续性心房颤动对肺静脉结构重构的影响及CT的评估价值研究[J].实用心脑肺血管病杂志,2015,23(3):77-79.DOI:10.3969/j.issn.1008-5971.2015.03.025.2019-09-102019-11-20
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