张航,虞敏,谷彤彤,袁忠祥

• 1:南京医科大学附属上海市第一人民医院心脏及大血管外科
• 2:南京医科大学附属南京市第一医院中心实验室

摘要(Abstract)：

急性肺损伤(ALI)是一种急性肺部炎性损伤性疾病,是心脏外科术后常见并发症之一,以肺泡上皮细胞及毛细血管内皮细胞损伤为主要病理特征,主要临床表现为急性低氧性呼吸功能不全。ALI可进展为急性呼吸窘迫综合征(ARDS),病死率为27%～45%,严重威胁患者生命安全及生存质量。近年来,大量研究发现ALI患者血清及支气管肺泡灌洗液(BALF)中存在多种生物标志物。本文通过检索国内外相关文献,综述了心脏外科术后ALI主要生物标志的研究进展,以期为ALI的早期诊断提供参考。

关键词(KeyWords)： 急性肺损伤;心脏外科手术;生物标志物;综述

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金青年科学基因项目(81300094)

作者(Author): 张航,虞敏,谷彤彤,袁忠祥

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