张效明;张鹏;王廷涛;冯崴;

• 1:蚌埠医学院第二附属医院心血管内科

摘要(Abstract)：

目的探讨老年慢性心力衰竭(CHF)患者血浆脑钠肽前体(NT-proBNP)水平与左室功能的关系及临床意义。方法将93例老年CHF患者按美国心脏病协会(NYHA)分级方法分为心功能Ⅱ、Ⅲ、Ⅳ级3组,25名健康老年人纳入对照组。采用电化学发光免疫分析技术测定4组血浆NT-proBNP水平,用超声心动图测定左室舒张末期内径(LVEDD)和左心室射血分数(LVEF)。结果心力衰竭NT-proBNP、LVEDD显著高于对照组(P<0.01),且血清NT-proBNP浓度随着心功能分级的增加而升高(3组两两比较均有统计学意义,P<0.01)。NT-proBNP水平与LVEDD呈正相关(r=0.711,P<0.01),而与LVEF呈负相关(r=-0.85,P<0.01)。结论血浆NT-proBNP水平可作为CHF患者心功能检测的有效生化指标,可以用来评估老年心力衰竭患者的左室功能。

关键词(KeyWords)： 心力衰竭,充血性;心室功能,左;超声心动描记术

Abstract:

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作者(Author): 张效明;张鹏;王廷涛;冯崴;

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参考文献(References)：

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